Where Dog Breed fantasy Goes to Die.
Primary hyperoxaluria type I is an inherited metabolic disorder causing excessive oxalate production and calcium oxalate crystal deposition, leading to recurrent urolithiasis, renal tubular injury, and progressive kidney damage.
Comments closedPyruvate kinase deficiency is an inherited erythrocyte enzyme disorder that impairs red blood cell energy metabolism, causing chronic hemolytic anemia and, in some breeds, progressive systemic complications.
Comments closedScotty cramp is an inherited paroxysmal movement disorder associated with abnormal neuromuscular control, causing episodic gait changes, muscle cramping, hyperflexion, hyperextension, and stress- or excitement-triggered motor episodes.
Comments closedShar-Pei autoinflammatory disease is a breed-associated inflammatory syndrome characterized by recurrent fever episodes, hock swelling or pain, systemic inflammation, and increased risk of reactive amyloidosis affecting organs such as the kidneys.
Comments closedTarsal hyperextension is abnormal overextension or instability of the hock joint caused by ligament, tendon, or joint support failure, leading to a dropped-hock stance, abnormal gait, pain, and reduced limb function.
Comments closedTracheal hypoplasia is congenital underdevelopment and narrowing of the tracheal lumen, resulting in reduced airway diameter, increased airflow resistance, and variable respiratory compromise.
Comments closedUpper airway syndrome is an obstructive respiratory disorder involving abnormal upper airway structure or function, causing increased airway resistance, noisy breathing, exercise intolerance, respiratory distress, and variable collapse risk.
Comments closedUrinary incontinence is involuntary leakage of urine caused by impaired urine storage or urethral closure, often related to urethral sphincter mechanism incompetence, congenital urinary tract abnormalities, neurologic disease, infection, stones, or other urinary disorders.
Comments closedVan den Ende-Gupta syndrome is a rare inherited skeletal and craniofacial developmental disorder associated with SCARF2 variants, causing abnormal facial structure, joint contractures, limb and skeletal abnormalities, and breed-specific congenital orthopedic concerns.
Comments closedSeborrhea is a keratinization disorder of the skin characterized by abnormal scaling, greasiness, flaking, odor, inflammation, and variable secondary bacterial or yeast infection.
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