Archives: Health Watch

Glaucoma is a group of ocular diseases characterized by pathologic elevation of intraocular pressure sufficient to damage the optic nerve and retina, causing pain and potentially irreversible vision loss.

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Hereditary cataracts are genetically influenced lens opacities that occur independently of trauma, diabetes, or age-related change and may appear in juvenile, adult-onset, progressive, or breed-specific patterns.

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Primary lens luxation is an inherited weakening or rupture of the lens zonular fibers that allows the ocular lens to partially or completely dislocate from its normal position, often causing inflammation, glaucoma, pain, and vision loss.

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MDR1-related drug sensitivity is a pharmacogenetic condition caused by variants in the ABCB1 gene that reduce P-glycoprotein function, allowing certain medications to accumulate in the central nervous system and cause toxicity.

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Primary angle-closure glaucoma is an inherited form of glaucoma in which the iridocorneal drainage angle narrows or closes, obstructing aqueous humor outflow and causing elevated intraocular pressure, pain, optic nerve damage, and rapid vision loss.

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Collie eye anomaly is a congenital inherited ocular developmental disorder involving choroidal hypoplasia and variable defects of the retina, sclera, and optic nerve that can range from clinically mild changes to coloboma, retinal detachment, hemorrhage, and blindness.

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Myxomatous mitral valve disease is a degenerative valvular disease in which the mitral valve leaflets and chordae tendineae thicken and deform, causing mitral regurgitation, left atrial and ventricular enlargement, and possible congestive heart failure.

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Retinal dysplasia is abnormal development and organization of the retinal tissue, producing retinal folds, geographic lesions, or complete retinal detachment, with visual impact ranging from none to blindness depending on severity.

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Entropion is inward rolling of an eyelid margin that causes eyelashes, hair, or eyelid skin to rub against the cornea and conjunctiva, leading to irritation, pain, ulceration, scarring, and possible vision damage.

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Early-onset adult deafness is inherited progressive sensorineural hearing loss that develops after puppyhood and causes declining auditory function in young to middle-aged adult dogs.

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